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There are 3 four-letter words containing YME

CYME	• cyme n. (Obsolete, rare) A “head” (Of unexpanded leaves, etc.); an opening bud. • cyme n. (Botany) A flattish or convex flower cluster, of the centrifugal or determinate type, on which each… • cyme n. (Architecture) = cyma.
LYME	• lyme v. (Jamaica, slang) to hang out (to spend time doing nothing in particular). • Lyme prop.n. A town in New London County, Connecticut, United States. • Lyme prop.n. A town in Grafton County, New Hampshire, United States.
ZYME	• zyme n. A ferment. • zyme n. (Obsolete, medicine) The morbific principle of a zymotic disease. • ZYME n. a ferment.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 10 words
Scrabble in French: 1 word
Scrabble in Spanish: 2 words
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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