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There are 15 eleven-letter words containing UPI

BUPIVACAINEbupivacaine n. (Pharmacology) A local anesthetic C18H28N2O that is like lidocaine in its action but is longer acting.
BUPIVACAINE n. a local anaesthetic of long duration, used for nerve blocks.
CHIRRUPIESTCHIRRUPY adj. cheerful.
KETCHUPIESTKETCHUPY adj. of or like ketchup.
OWERLOUPINGOWERLOUP v. (Scots) to leap over, also OVERLEAP.
PORCUPINIERPORCUPINY adj. like a porcupine, a large spiny rodent of various kinds.
PORCUPINISHporcupinish adj. Resembling or characteristic of a porcupine or its spines; defensive, prickly.
PORCUPINISH adj. like a porcupine.
PREOCCUPIEDpreoccupied adj. Concerned with something else; distracted; giving one’s attention elsewhere.
preoccupied adj. (Taxonomy, not comparable) Describing a scientific name that was previously used, a junior homonym.
preoccupied v. Simple past tense and past participle of preoccupy.
PREOCCUPIESpreoccupies v. Third-person singular simple present indicative form of preoccupy.
PREOCCUPY v. to engross or fill the mind of.
PUPILLARITYpupillarity n. (Scotland, law) The period before puberty, or from birth to fourteen in males, and twelve in females.
pupillarity n. Pupilage.
PUPILLARITY n. the state of being a pupil or legal ward, also PUPILARITY.
PUPILLATINGPUPILLATE v. to cry in the manner of a peacock.
REGROUPINGSregroupings n. Plural of regrouping.
REGROUPING n. the act of forming a new group.
SOUPINESSESSOUPINESS n. the quality of being soupy.
STUPIDITIESstupidities n. Plural of stupidity.
STUPIDITY n. the quality of being stupid.
SUBGROUPINGsubgrouping v. Present participle of subgroup.
subgrouping n. A subgroup.
SUBGROUP v. to divide into subgroups.
SUPINATIONSsupinations n. Plural of supination.
SUPINATION n. being turned upward.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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