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There are 14 ten-letter words containing UPR

BUPRESTIDSbuprestids n. Plural of buprestid.
BUPRESTID n. a kind of wood-boring beetle.
BUPROPIONSBUPROPION n. an antidepressant drug used in the treatment of nicotine addiction.
IBUPROFENSibuprofens n. Plural of ibuprofen.
IBUPROFEN n. an anti-inflammatory drug.
STUPRATINGstuprating v. Present participle of stuprate.
STUPRATE v. (archaic) to ravish; to violate.
STUPRATIONstupration n. (Obsolete) Rape.
STUPRATION n. (archaic) rape, violation.
SUPRALUNARsupralunar adj. Beyond the Moon; hence, very lofty.
SUPRALUNAR adj. beyond the moon; very lofty.
SUPRAOPTICsupraoptic adj. (Anatomy) Above the optic tract or chiasma.
SUPRAOPTIC adj. situated above the optic chiasma.
SUPRAPUBICsuprapubic adj. (Anatomy) Above, or anterior to, the pubic bone.
supra-pubic adj. Alternative spelling of suprapubic.
SUPRAPUBIC adj. situated above, or anterior to, the pubic bone.
SUPRARENALsuprarenal adj. Located on, or above the kidney.
suprarenal n. A suprarenal capsule.
SUPRARENAL adj. situated above, or anterior to, the kidneys.
SUPRAVITALsupravital adj. (Cytology, of a stain) Capable of staining living cells after their removal from a host.
SUPRAVITAL adj. relating to the staining of living tissues.
UPREACHINGupreaching v. Present participle of upreach.
UPREACH v. to reach up.
UPRIGHTINGuprighting v. Present participle of upright.
UPRIGHT v. to raise or restore to an upright position.
UPROARIOUSuproarious adj. Causing, or likely to cause, an uproar.
uproarious adj. Characterized by uproar, that is, loud, confused noise, or by noisy and uncontrollable laughter.
uproarious adj. (By extension) Extremely funny; hilarious.
UPROOTINGSuprootings n. Plural of uprooting.
UPROOTING n. the act of uprooting.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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