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There are 3 eight-letter words containing TRILE

LAETRILElaetrile n. A drug, derived from the amygdalin of apricot kernels, once thought capable of destroying cancer cells…
LAETRILE n. (tradename) a drug derived from apricot pits, used in the treatment of cancer.
NITRILESnitriles n. Plural of nitrile.
NITRILE n. any organic cyanide compound in which an alkyl group is directly attached to the carbon of a cyanide group, also NITRIL.
TRILEMMAtrilemma n. A circumstance in which a choice must be made between three options that seem equally undesirable.
trilemma n. A situation in which a choice must be made among three desirable options, only two of which are possible…
trilemma n. (Logic) An argument containing three alternatives, jointly exhaustive either under any condition(s)…

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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