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There are 4 twelve-letter words containing TISP

ANTISPASTICSantispastics n. Plural of antispastic.
ANTISPASTIC n. a substance that prevents or reduces spasms.
ANTISPENDINGantispending adj. (Politics) Opposed to or combating spending, especially government spending.
ANTISPENDING adj. opposed to spending.
FRONTISPIECEfrontispiece n. (Publishing) An illustration that is on the page before the title page of a book, a section of one, or a magazine.
frontispiece n. (Archaic, publishing) The title page of a book.
frontispiece n. (Architecture) A façade, especially an ornamental one.
MULTISPECIESmultispecies adj. Comprising or involving more than one species.
MULTISPECIES adj. comprising many species.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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