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There are 10 five-letter words containing TIR

ASTIRastir adj. In motion; characterized by motion.
astir adj. Out of bed; up and about.
ASTIR adj. on the move.
STIRESTIRE v. (archaic) to stir, also STYRE.
STIRKstirk n. (Britain, Scotland, dialectal, dated) A yearling cow; a young bullock or heifer.
STIRK n. a yearling ox or cow.
STIRPstirp n. (Biology, anthropology) A line descended from a single ancestor.
stirp n. (Systematics) A line descending from a single extant ancestor, a lineage descending from a supergenerative species.
STIRP n. a branch of a family; pedigree, also STIRPS.
STIRSstirs n. Plural of stir.
stirs v. Third-person singular simple present indicative form of stir.
STIRs n. Plural of STIR.
TIREDtired v. Simple past tense and past participle of tire.
tired adj. In need of some rest or sleep.
tired adj. Fed up, annoyed, irritated, sick of.
TIREStires n. Plural of tire.
tires v. Third-person singular simple present indicative form of tire.
TIRE v. to grow tired.
TIRLStirls v. Third-person singular simple present indicative form of tirl.
TIRL v. (Scots) to turn; to rattle, also DIRL, THIRL.
TIROStiros n. Plural of tiro.
TIRO n. (Latin) a beginner or novice, also TYRO.
TIRRSTIRR v. (Scots) to strip.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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