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There are 17 twelve-letter words containing TUP

CENTUPLICATEcentuplicate v. To make a hundredfold; to repeat or multiply a hundred times.
CENTUPLICATE v. to centuple.
CONSTUPRATEDconstuprated v. Simple past tense and past participle of constuprate.
CONSTUPRATE v. (obsolete) to ravish.
CONSTUPRATESconstuprates v. Third-person singular simple present indicative form of constuprate.
CONSTUPRATE v. (obsolete) to ravish.
OCTUPLICATESoctuplicates n. Plural of octuplicate.
OCTUPLICATE n. one of eight corresponding things.
SEPTUPLICATEseptuplicate adj. Seven times the number, volume, length, etc. (of something else); septuple.
septuplicate v. To multiply by seven; to septuple.
SEPTUPLICATE n. a group of seven things.
SEXTUPLICATEsextuplicate adj. Six times the number, volume, length, etc. (of something else).
sextuplicate adj. Comprising six identical parts.
sextuplicate n. A series, set, collection, or group of six identical copies of something.
STUPEFACIENTstupefacient adj. (Medicine) Inducing stupor or drowsiness (with a drug such as a narcotic or an anaesthetic).
stupefacient n. (Medicine) Any drug that induces stupor or drowsiness.
STUPEFACIENT n. a narcotic, a stupefying drug.
STUPEFACTIONstupefaction n. The state of extreme shock or astonishment.
stupefaction n. A state of insensibility; stupor.
STUPEFACTION n. the act of stupefying.
STUPEFACTIVEstupefactive adj. Inducing stupor; making drowsy; stupefacient.
STUPEFACTIVE adj. causing stupefaction.
STUPEFYINGLYstupefyingly adv. In a stupefying manner.
STUPEFYING adv. STUPEFY, to dull the senses of.
STUPENDOUSLYstupendously adv. In a stupendous manner.
STUPENDOUS adv. causing astonishment or wonder, also STUPENDIOUS.
STUPIDNESSESstupidnesses n. Plural of stupidness.
STUPIDNESS n. the state of being stupid.
VITUPERATINGvituperating v. Present participle of vituperate.
VITUPERATE v. to abuse or censure severely or abusively.
VITUPERATIONvituperation n. The act of vituperating; severely blaming or censuring.
vituperation n. Criticism or invective that is sustained and overly harsh; abuse, severe blame or censure.
VITUPERATION n. abuse, rejection.
VITUPERATIVEvituperative adj. Marked by harsh, spoken, or written abuse; abusive, often with ranting or railing.
VITUPERATIVE adj. uttering or given to censure, also VITUPERATORY.
VITUPERATORSvituperators n. Plural of vituperator.
VITUPERATOR n. one who vituperates.
VITUPERATORYvituperatory adj. Vituperative.
VITUPERATORY adj. uttering or given to censure, also VITUPERATIVE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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