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There are 5 six-letter words containing SPIRE

ASPIRE	• aspire v. (Intransitive) To have a strong desire or ambition to achieve something. • aspire v. (Transitive, obsolete) To go as high as, to reach the top of (something). • aspire v. (Intransitive, archaic, literary) To move upward; to be very tall.
SPIREA	• spirea n. Any of the many flowering shrubs of the genus Spiraea, that have clusters of white or pink flowers. • spirea n. Any of the flowering plants of the genus Astilbe. • SPIREA n. (Greek) a group of plants, including hardhack and meadowsweet, also SPIRAEA.
SPIRED	• spired adj. Having a spire. • 'spired v. Simple past tense and past participle of ’spire. • SPIRE v. to rise in a tapering manner.
SPIREM	• spirem n. Alternative form of spireme. • SPIREM n. a filament forming part of a cell nucleus, also SPIREME.
SPIRES	• spires n. Plural of spire. • spires v. Third-person singular simple present indicative form of spire. • Spires prop.n. A surname.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

English Wiktionary: 8 words
Scrabble in French: 3 words
Scrabble in Spanish: 2 words
Scrabble in Italian: 2 words
Scrabble in German: no word
Scrabble in Romanian: 4 words

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