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There are 7 eight-letter words containing STIO

BASTIONSbastions n. Plural of bastion.
bastions v. Third-person singular simple present indicative form of bastion.
BASTION n. a tower at the corner of a fortification.
EGESTIONegestion n. The act or result of egesting.
EGESTION n. the process of excretion from the body.
HISTIOIDhistioid adj. Synonym of histoid.
HISTIOID adj. resembling the normal tissues; as, histioid tumors, also HISTOID.
INUSTIONinustion n. (Obsolete) The act of burning or branding.
INUSTION n. burning in.
OSTIOLARostiolar adj. Of or pertaining to the ostiole.
OSTIOLAR adj. relating to an ostiole, a small opening.
OSTIOLESostioles n. Plural of ostiole.
OSTIOLE n. a small bodily opening.
QUESTIONquestion n. A sentence, phrase or word which asks for information, reply or response; an interrogative.
question n. A subject or topic for consideration or investigation.
question n. A doubt or challenge about the truth, accuracy, or validity of a matter.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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