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There are 4 seven-letter words containing SPAI

DESPAIRdespair v. (Transitive, obsolete) To give up as beyond hope or expectation; to despair of.
despair v. (Transitive) To cause to despair.
despair v. (Intransitive, often with “of”) To be hopeless; to have no hope; to give up all hope or expectation.
SPAINEDSPAIN v. (Scots) to wean, also SPANE, SPEAN.
SPAINGSSPAING n. staying at a spa.
SPAIRGESPAIRGE v. to sprinkle (with moisture), also SPARGE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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