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There are 5 six-letter words containing SSIS

ASSIST	• assist v. To help. • assist v. (Sports) To make a pass that leads directly towards scoring. • assist v. (Medicine) To help compensate for what is missing with the help of a medical technique or therapy.
CASSIS	• cassis n. The blackcurrant plant, Ribes nigrum; the flavor of its berries. • cassis n. A liqueur made from these berries, especially crème de cassis. • cassis n. (Chiefly US) A wine flavor note, suggesting the fruity and full-bodied characteristics of the fruit;…
LASSIS	• lassis n. Plural of lassi. • LASSI n. (Hindi) a drink based on sour milk, popular in the East.
MISSIS	• missis n. (US, historical, colloquial) Pronunciation spelling of missus, representing African American Vernacular… • MISSIS n. (colloquial) wife, also MISSUS.
TUSSIS	• tussis n. A cough. • TUSSIS n. (Latin) a cough.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

English Wiktionary: 15 words
Scrabble in French: 7 words
Scrabble in Spanish: no word
Scrabble in Italian: 6 words
Scrabble in German: 6 words
Scrabble in Romanian: no word

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