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There are 9 six-letter words containing SPIR

ASPIREaspire v. (Intransitive) To have a strong desire or ambition to achieve something.
aspire v. (Transitive, obsolete) To go as high as, to reach the top of (something).
aspire v. (Intransitive, archaic, literary) To move upward; to be very tall.
SPIRALspiral n. (Geometry) A curve that is the locus of a point that rotates about a fixed point while continuously…
spiral n. (Informal) A helix.
spiral n. A self-sustaining process with a lot of momentum involved, so it is difficult to accelerate or stop it at once.
SPIREAspirea n. Any of the many flowering shrubs of the genus Spiraea, that have clusters of white or pink flowers.
spirea n. Any of the flowering plants of the genus Astilbe.
SPIREA n. (Greek) a group of plants, including hardhack and meadowsweet, also SPIRAEA.
SPIREDspired adj. Having a spire.
'spired v. Simple past tense and past participle of ’spire.
SPIRE v. to rise in a tapering manner.
SPIREMspirem n. Alternative form of spireme.
SPIREM n. a filament forming part of a cell nucleus, also SPIREME.
SPIRESspires n. Plural of spire.
spires v. Third-person singular simple present indicative form of spire.
Spires prop.n. A surname.
SPIRICspiric adj. Like a torus.
spiric n. (Geometry) A curve, the plane section of a torus.
SPIRIC n. a curve, the plane section of a tore.
SPIRITspirit n. The soul of a person or other creature.
spirit n. A supernatural being, often but not exclusively without physical form; ghost, fairy, angel.
spirit n. Enthusiasm.
SPIRTSspirts v. Third-person singular simple present indicative form of spirt.
spirts n. Plural of spirt.
SPIRT v. to emit liquid forcibly, also SPURT.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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