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There are 17 twelve-letter words containing SPLE

DISPLEASANCEdispleasance n. (Obsolete) Displeasure, dissatisfaction.
DISPLEASANCE n. (Spenser) displeasure.
DISPLEASANTSDISPLEASANT v. to render unpleasing.
DISPLEASEDLYdispleasedly adv. In a displeased manner.
DISPLEASED adv. DISPLEASE, to offend, to annoy.
DISPLEASUREDdispleasured v. Simple past tense and past participle of displeasure.
DISPLEASURE v. (archaic) to displease.
DISPLEASURESdispleasures n. Plural of displeasure.
DISPLEASURE v. (archaic) to displease.
DISPLENISHEDdisplenished v. Simple past tense and past participle of displenish.
DISPLENISH v. to deprive or strip, as a house of furniture, or a barn of stock.
DISPLENISHESdisplenishes v. Third-person singular simple present indicative form of displenish.
DISPLENISH v. to deprive or strip, as a house of furniture, or a barn of stock.
MISPLEADINGSmispleadings n. Plural of mispleading.
MISPLEADING n. an error in pleading.
RESPLENDENCEresplendence n. The property of being, or that which causes something to be, resplendent.
RESPLENDENCE n. the state of being resplendent, also RESPLENDENCY.
RESPLENDENCYresplendency n. Resplendence, radiant beauty.
resplendency n. (Mathematics) A property of the truth of sentence structures in Peano arithmetic.
RESPLENDENCY n. the state of being resplendent, also RESPLENDENCE.
SPLEENSTONESspleen␣stones n. Plural of spleen stone.
SPLEENSTONE n. (obsolete) jade.
SPLENDIDIOUSsplendidious adj. (Obsolete) splendid.
SPLENDIDIOUS adj. (obsolete) splendid, also SPLENDIDOUS.
SPLENDIDNESSsplendidness n. The state or the quality of being splendid.
splendidness n. Something that is splendid.
SPLENDIDNESS n. the state of being splendid.
SPLENISATIONsplenisation n. Britain standard spelling of splenization.
SPLENISATION n. conversion (e.g. of the lung) into a spongy, spleen-like substance, also SPLENIZATION.
SPLENIZATIONsplenization n. (Medicine) A morbid state of the lung produced by inflammation, in which its tissue resembles that of the spleen.
SPLENIZATION n. conversion (e.g. of the lung) into a spongy, spleen-like substance, also SPLENISATION.
SPLENOMEGALYsplenomegaly n. (Pathology) An enlargement of the spleen.
SPLENOMEGALY n. abnormal enlargement of the spleen.
SPORTSPLEXESsportsplexes n. Plural of sportsplex.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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