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There are 20 fifteen-letter words containing SIG

ASSIGNABILITIESASSIGNABILITY n. the quality of being assignable.
COSIGNIFICATIVEcosignificative adj. (Rare) Having the same meaning.
COSIGNIFICATIVE adj. having the same signification.
FORESIGHTEDNESSforesightedness n. The quality of having foresight.
foresightedness n. The prudent exercise of common sense when planning for the future.
FORESIGHTEDNESS n. the state of being foresighted.
INSIGNIFICANCESinsignificances n. Plural of insignificance.
INSIGNIFICANCE n. the state of being insignificant, also INSIGNIFICANCY.
INSIGNIFICANTLYinsignificantly adv. In an insignificant manner, or to a degree that does not matter.
INSIGNIFICANT adv. not significant.
INSIGNIFICATIVEinsignificative adj. Not expressing meaning; not significant.
INSIGNIFICATIVE adj. not significative or expressing by external signs.
INTRANSIGEANCESintransigeances n. Plural of intransigeance.
INTRANSIGEANCE n. the state of being intransigeant, also INTRANSIGENCE, INTRANSIGENCY.
INTRANSIGEANTLYintransigeantly adv. Alternative form of intransigently.
INTRANSIGEANT adv. intransigent.
INTRANSIGENCIESINTRANSIGENCY n. the state of being intransigent, also INTRANSIGEANCE, INTRANSIGENCE.
INTRANSIGENTISMintransigentism n. The principles of intransigents; refusal to compromise.
INTRANSIGENTISM n. a policy of being intransigent.
INTRANSIGENTISTintransigentist n. A person who refuses to compromise on their position.
INTRANSIGENTIST n. a supporter of intransigentism.
LONGSIGHTEDNESSlongsightedness n. Farsight; farsightedness; far sight; long sight.
LONGSIGHTEDNESS n. the state of being longsighted.
NEARSIGHTEDNESSnearsightedness n. The property of being nearsighted, myopia.
near-sightedness n. Alternative spelling of nearsightedness.
NEARSIGHTED n. able to see near things more clearly than distant ones.
NONSIGNIFICANTSNONSIGNIFICANT n. (in cryptography) a symbol or sign without meaning.
PREDESIGNATIONSpredesignations n. Plural of predesignation.
PREDESIGNATION n. the act of predesignating.
SIGHTLESSNESSESSIGHTLESSNESS n. the state of being sightless.
SIGMOIDECTOMIESsigmoidectomies n. Plural of sigmoidectomy.
SIGMOIDECTOMY n. removal of the sigmoid colon.
SIGMOIDOSCOPIESsigmoidoscopies n. Plural of sigmoidoscopy.
SIGMOIDOSCOPY n. examination of the interior of the rectum and sigmoid colon.
SIGNIFICATIVELYsignificatively adv. In a significative manner.
SIGNIFICATIVE adv. significant, suggestive.
UNSIGHTLINESSESunsightlinesses n. Plural of unsightliness.
UNSIGHTLINESS n. the state of being unsightly.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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