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There are 4 fourteen-letter words containing SIGNIFICAN

INSIGNIFICANCE	• insignificance n. The state of being insignificant. • INSIGNIFICANCE n. the state of being insignificant, also INSIGNIFICANCY.
INSIGNIFICANCY	• insignificancy n. (Obsolete) Lack of signification; meaninglessness. • insignificancy n. Unimportance, insignificance. • insignificancy n. An insignificant person or thing.
NONSIGNIFICANT	• nonsignificant adj. (Sciences) Lacking statistical significance. • NONSIGNIFICANT n. (in cryptography) a symbol or sign without meaning.
SIGNIFICANCIES	• significancies n. Plural of significancy. • SIGNIFICANCY n. significance.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 6 words
Scrabble in French: no word
Scrabble in Spanish: 1 word
Scrabble in Italian: 4 words
Scrabble in German: no word
Scrabble in Romanian: no word

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