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There are 7 five-letter words containing RAIN

BRAINbrain n. The control center of the central nervous system of an animal located in the skull which is responsible…
brain n. (Informal) An intelligent person.
brain n. (In the plural) Intellect.
DRAINdrain n. (Chiefly US, Canada) A conduit allowing liquid to flow out of an otherwise contained volume; a plughole (UK).
drain n. (Chiefly UK) An access point or conduit for rainwater that drains directly downstream in a (drainage)…
drain n. Something consuming resources and providing nothing in return.
GRAINgrain n. (Uncountable) The harvested seeds of various grass food crops eg: wheat, corn, barley.
grain n. (Uncountable) Similar seeds from any food crop, e.g., buckwheat, amaranth, quinoa.
grain n. (Countable) A single seed of grass food crops.
RAINEraine n. Obsolete form of rain.
Raine prop.n. A surname transferred from the given name derived from any of several personal names (such as Raymond).
RAINE v. (Spenser) to reign, also RAYNE.
RAINSrains n. Plural of rain.
rains n. A rainy season; monsoon.
rains v. Third-person singular simple present indicative form of rain.
RAINYrainy adj. Pouring with rain; wet; showery.
RAINY adj. marked by rain.
TRAINtrain n. Elongated or trailing portion.
train n. Connected sequence of people or things.
train v. (Intransitive) To practice an ability.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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