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There are 8 six-letter words containing PIRE

ASPIREaspire v. (Intransitive) To have a strong desire or ambition to achieve something.
aspire v. (Transitive, obsolete) To go as high as, to reach the top of (something).
aspire v. (Intransitive, archaic, literary) To move upward; to be very tall.
EMPIREempire n. A political unit, typically having an extensive territory or comprising a number of territories or nations…
empire n. A political unit ruled by an emperor or empress.
empire n. The group of states or other territories that owe allegiance to an imperial power (foreign to them)…
EXPIREexpire v. (Intransitive) To die.
expire v. (Intransitive) To lapse and become invalid.
expire v. (Intransitive) To come to an end; to conclude.
SPIREAspirea n. Any of the many flowering shrubs of the genus Spiraea, that have clusters of white or pink flowers.
spirea n. Any of the flowering plants of the genus Astilbe.
SPIREA n. (Greek) a group of plants, including hardhack and meadowsweet, also SPIRAEA.
SPIREDspired adj. Having a spire.
'spired v. Simple past tense and past participle of ’spire.
SPIRE v. to rise in a tapering manner.
SPIREMspirem n. Alternative form of spireme.
SPIREM n. a filament forming part of a cell nucleus, also SPIREME.
SPIRESspires n. Plural of spire.
spires v. Third-person singular simple present indicative form of spire.
Spires prop.n. A surname.
UMPIREumpire n. (Tennis, badminton) The official who presides over a tennis match sat on a high chair.
umpire n. (Cricket) One of the two white-coated officials who preside over a cricket match.
umpire n. (Baseball) One of the officials who preside over a baseball game.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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