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There are 13 twelve-letter words containing OPTIM

OPTIMALISING	• optimalising v. Present participle of optimalise. • OPTIMALISE v. to bring to the most desirable or most efficient state, also OPTIMALIZE.
OPTIMALITIES	• optimalities n. Plural of optimality. • OPTIMALITY n. the state of being optimal.
OPTIMALIZING	• optimalizing v. Present participle of optimalize. • OPTIMALIZE v. to bring to the most desirable or most efficient state, also OPTIMALISE.
OPTIMISATION	• optimisation n. Alternative spelling of optimization. • OPTIMISATION n. the act of optimising, also OPTIMIZATION.
OPTIMISTICAL	• optimistical adj. Optimistic. • OPTIMISTICAL adj. optimistic, also OPTIMISTIC.
OPTIMIZATION	• optimization n. The design and operation of a system or process to make it as good as possible in some defined sense. • optimization n. (Programming) The reduction of a program or algorithm to its most efficient form, as during compilation… • OPTIMIZATION n. the act of optimizing, also OPTIMISATION.
OVEROPTIMISM	• overoptimism n. Excessive optimism. • OVEROPTIMISM n. excessive optimism.
OVEROPTIMIST	• overoptimist n. An excessively optimistic person. • OVEROPTIMIST n. one who is excessively optimistic.
SUBOPTIMALLY	• suboptimally adv. In a less than optimal manner.
SUBOPTIMISED	• SUBOPTIMISE v. to optimize to an inferior degree, also SUBOPTIMIZE.
SUBOPTIMISES	• SUBOPTIMISE v. to optimize to an inferior degree, also SUBOPTIMIZE.
SUBOPTIMIZED	• suboptimized v. Simple past tense and past participle of suboptimize. • SUBOPTIMIZE v. to optimize to an inferior degree, also SUBOPTIMISE.
SUBOPTIMIZES	• suboptimizes v. Third-person singular simple present indicative form of suboptimize. • SUBOPTIMIZE v. to optimize to an inferior degree, also SUBOPTIMISE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 29 words
Scrabble in French: 17 words
Scrabble in Spanish: 9 words
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: 12 words

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