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There are 4 twelve-letter words containing OSEM

CLOSEMOUTHEDclosemouthed adj. Reticent, secretive or uncommunicative.
CLOSEMOUTHED adj. cautious in speaking.
GALACTOSEMIAgalactosemia n. (Medicine) A genetic metabolic disorder characterized by an inability to metabolize galactose properly.
galactosemia n. The presence of galactose in the blood.
GALACTOSEMIA n. the presence of galactose in the blood, also GALACTOSAEMIA.
GALACTOSEMICgalactosemic n. One who has galactosemia.
galactosemic adj. Having or relating to galactosemia.
GALACTOSEMIC adj. relating to galactosemia, the presence of galactose in the blood, also GALACTOSAEMIC.
TSCHERNOSEMStschernosems n. Plural of tschernosem.
TSCHERNOSEM n. (Russian) a very fertile soil of subhumid steppe, also CHERNOZEM.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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