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There are 10 twelve-letter words containing OPSI

AMPELOPSISESampelopsises n. Plural of ampelopsis.
AMPELOPSIS n. a woody vine.
CERATOPSIANSceratopsians n. Plural of ceratopsian.
CERATOPSIAN n. a bird-hipped, plant-eating dinosaur of the late Cretaceous.
CHROMATOPSIAchromatopsia n. A visual aberration in which objects appear abnormally coloured, such as xanthopsia or cyanopia.
CHROMATOPSIA n. coloured vision.
ERYTHROPSIASERYTHROPSIA n. a defect of vision in which objects appear red.
HEMIANOPSIAShemianopsias n. Plural of hemianopsia.
HEMIANOPSIA n. a defect of vision in consequence of which a person sees but half of an object looked at, also HEMIANOPIA, HEMIOPIA, HEMIOPSIA.
ICHTHYOPSIDSICHTHYOPSID n. a member of the Ichthyopsida, amphibians, fishes and fishlike vertebrates, also ICHTHYOPSIDAN.
LOPSIDEDNESSlopsidedness n. The state or property of being lopsided.
LOPSIDEDNESS n. the state of being lopsided.
PHALAENOPSISphalaenopsis n. (Botany) Any of the genus Phalaenopsis of moth orchids.
Phalaenopsis prop.n. A taxonomic genus within the family Orchidaceae – moth orchids.
PORPHYROPSINporphyropsin n. Any of a group of purple carotenoid pigments, similar to rhodopsin, in the retinas of some fish.
PORPHYROPSIN n. a purple pigment in the retinal rods of freshwater fishes that resembles rhodopsin.
SAUROPSIDANSsauropsidans n. Plural of sauropsidan.
SAUROPSIDAN n. a member of the Sauropsida, one of the main divisions of Vertebrata including birds and reptiles.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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