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There are 4 twelve-letter words containing OPOT

ANTHROPOTOMYanthropotomy n. The anatomy or dissection of the human body; androtomy.
ANTHROPOTOMY n. human anatomy.
HIPPOPOTAMIChippopotamic adj. Of or relating to a hippopotamus.
HIPPOPOTAMIC adj. like a hippopotamus, clumsy, also HIPPOPOTAMIAN.
HIPPOPOTAMUShippopotamus n. A large, semi-aquatic, herbivorous (plant-eating) African mammal (Hippopotamus amphibius; common hippopotamus).
hippopotamus n. Any similar animal of the family Hippopotamidae.
Hippopotamus prop.n. A taxonomic genus within the family Hippopotamidae – hippopotamuses.
OPOTHERAPIESOPOTHERAPY n. treatment by administration of extracts of animal organs, esp. ductless glands.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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