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There are 14 twelve-letter words containing OPLE

ANCHORPEOPLEanchorpeople n. Plural of anchorperson.
ANCHORPERSON n. an anchorman or anchorwoman.
APOPLECTICALapoplectical adj. Alternative form of apoplectic.
APOPLECTICAL adj. (archaic) apoplectic, also APOPLECTIC.
CARDIOPLEGIAcardioplegia n. (Surgery) The deliberate, temporary cessation of cardiac activity before heart surgery.
CARDIOPLEGIA n. deliberate arrest of the action of the heart, as by hypothermia or the injection of chemicals, to enable complex heart surgery to be carried out.
CHURCHPEOPLEchurchpeople n. Plural of churchperson.
Church␣People n. Synonym of Fancy Dutch.
CHURCHPEOPLE n. people who attend church.
CRAFTSPEOPLEcraftspeople n. Plural of craftsperson.
CRAFTSPEOPLE n. workers who practice a trade or craft.
CYCLOPLEGIAScycloplegias n. Plural of cycloplegia.
CYCLOPLEGIA n. loss of visual accommodation because of ciliary muscle paralysis.
DRAFTSPEOPLEdraftspeople n. Plural of draftsperson.
SOMATOPLEUREsomatopleure n. (Embryology) A fold of tissue, in the embryo of a vertebrate, from which the walls of the body and the amnion develop.
SOMATOPLEURE n. a cellular sheet in some vertebrates that develops into the internal body wall.
SPOKESPEOPLEspokespeople n. Plural of spokesperson.
SPOKESPEOPLE n. people serving as spokesmen or spokeswomen.
SPORTSPEOPLEsportspeople n. Plural of sportsperson.
SPORTSPEOPLE n. people who take part in sport.
TOWNSPEOPLESTOWNSPEOPLE n. the inhabitants of a town or city.
TRADESPEOPLEtradespeople n. Plural of tradesperson.
TRADESPEOPLE n. people engaged in trade.
TRIBESPEOPLEtribespeople n. The people who belong to a tribe.
tribespeople n. A tribal race of people.
TRIBESPEOPLE n. members of a tribe.
UNDERPEOPLEDunderpeopled adj. Short of people; underpopulated.
UNDERPEOPLED adj. underpopulated.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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