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There are 14 twelve-letter words containing OPEN

ALDOPENTOSESaldopentoses n. Plural of aldopentose.
ALDOPENTOSE n. a type of sugar.
CYCLOPENTANEcyclopentane n. (Organic chemistry) An alicyclic hydrocarbon, C5H10; a volatile inflammable liquid, sometimes used as…
CYCLOPENTANE n. a colourless insoluble cycloalkane found in petroleum and used mainly as a solvent.
ERYTHROPENIAerythropenia n. A decrease in the number of erythrocytes, associated with anemia.
ERYTHROPENIA n. diminution below the normal of the number of red cells in the blood.
LYMPHOPENIASlymphopenias n. Plural of lymphopenia.
LYMPHOPENIA n. an abnormally low level of lymphocytes in the blood.
NEUTROPENIASneutropenias n. Plural of neutropenia.
NEUTROPENIA n. an abnormal reduction in the number of neutrophils in the blood, as seen in certain anaemias and leukaemias.
OPENHANDEDLYopenhandedly adv. Alternative form of open-handedly.
open-handedly adv. In an open-handed manner.
OPENHANDED adv. generous.
PANCYTOPENIApancytopenia n. (Pathology) A reduction in the numbers of red blood cells, white blood cells and platelets in the blood.
PANCYTOPENIA n. an abnormal reduction in the number of erythrocytes, white blood cells, and blood platelets in the blood.
POLYPROPENESpolypropenes n. Plural of polypropene.
POLYPROPENE n. any of various thermoplastic plastics or fibers that are polymers of propylene, also POLYPROPYLENE.
PROPENSENESSpropenseness n. Alternative form of propensenesse.
PROPENSENESS n. the state of being propense.
PROPENSITIESpropensities n. Plural of propensity.
PROPENSITY n. an often intense natural inclination or preference.
SCOLOPENDRASscolopendras n. Plural of scolopendra.
SCOLOPENDRA n. a centipede of the genus Scolopendra of myriapods, including large tropical centipedes up to a foot in length.
SCOLOPENDRIDscolopendrid n. (Zoology) Any of the family Scolopendridae of centipedes.
SCOLOPENDRID n. any centipede of the family Scolopendridae.
SIDEROPENIASsideropenias n. Plural of sideropenia.
SIDEROPENIA n. deficiency of iron.
THIOPENTONESTHIOPENTONE n. an intravenous anaesthetic.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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