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There are 12 four-letter words containing OPE

COPEcope v. (Intransitive) To deal effectively with something, especially if difficult.
cope v. To cut and form a mitred joint in wood or metal.
cope v. (Falconry) To clip the beak or talons of a bird.
DOPEdope n. (Uncountable) Any viscous liquid or paste, such as a lubricant, used in preparing a surface.
dope n. (Uncountable) An absorbent material used to hold a liquid.
dope n. (Uncountable, aeronautics) Any varnish used to coat a part, such as an airplane wing or a hot-air balloon…
HOPEhope v. (Intransitive, transitive) To want something to happen, with a sense of expectation that it might.
hope v. To be optimistic; be full of hope; have hopes.
hope v. (Intransitive) To place confidence; to trust with confident expectation of good; usually followed by in.
LOPElope v. To travel an easy pace with long strides.
lope v. (Obsolete, intransitive) To jump, leap.
lope n. An easy pace with long strides.
MOPEmope v. (Intransitive) To carry oneself in a depressed, lackadaisical manner; to give oneself up to low spirits;…
mope v. (Transitive) To make spiritless and stupid.
mope n. The act of moping.
NOPEnope part. (Informal, often emphatic) No.
nope n. (Informal) A negative reply, no.
nope n. (Slang) An intensely undesirable thing, such as a circumstance or an animal, eliciting immediate repulsion…
OPEDoped v. Simple past tense and past participle of ope.
op-ed n. A newspaper page containing signed articles by commentators expressing viewpoints that may not agree…
op-ed adj. Of or being a newspaper page, usually opposite the editorial page, that features signed articles expressing…
OPENopen adj. (Usually not comparable) Not closed.
open adj. Not physically drawn together, closed, folded or contracted; extended.
open adj. (Not comparable) Actively conducting or prepared to conduct business.
OPESopes v. Third-person singular simple present indicative form of ope.
OPE v. to open.
POPEpope n. (Roman Catholicism and generally) An honorary title of the Roman Catholic bishop of Rome as father and…
pope n. (Coptic Church) An honorary title of the Coptic bishop of Alexandria as father and head of his church.
pope n. (Eastern Orthodoxy) An honorary title of the Orthodox bishop of Alexandria as father and head of his…
ROPErope n. (Uncountable) Thick strings, yarn, monofilaments, metal wires, or strands of other cordage that are…
rope n. (Countable) An individual length of such material.
rope n. A cohesive strand of something.
TOPEtope v. (Archaic) To drink excessively; to get drunk.
tope n. A small, grey, European shark, Galeorhinus galeus, that has rough skin and a long snout.
tope n. (India) A grove of trees.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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