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There are 2 fifteen-letter words containing NESTE

CHOLINESTERASEScholinesterases n. Plural of cholinesterase.
CHOLINESTERASE n. an enzyme which breaks down a choline ester into choline and an acid, esp. acetylcholine into choline and acetic acid.
PECTINESTERASESpectinesterases n. Plural of pectinesterase.
PECTINESTERASE n. an enzyme that catalyzes the hydrolysis of pectins into pectic acids and methanol.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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