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There are 4 eight-letter words containing LASTO

ALASTORSalastors n. Plural of alastor.
ALASTOR n. (Greek) an avenging deity in Greek tragedy.
BLASTOFFblastoff n. The countdown and launch of a rocket, missile or spacecraft.
blast-off n. Alternative spelling of blastoff.
blast␣off v. (Idiomatic, intransitive) to begin ascent under rocket power.
BLASTOIDblastoid n. (Paleontology) A member of an extinct class of echinoderms, the Blastoidea.
blastoid n. (Medicine) A blastocyst grown in-vitro.
blastoid adj. (Paleontology) Of or relating to blastoids.
BLASTOMAblastoma n. (Pathology) A tumour that is caused by malignancies in precursor cells or blasts.
BLASTOMA n. a type of tumour.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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