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There are 4 eight-letter words containing LOTO

COLOTOMYcolotomy n. (Surgery, medicine) Any incisional operation on the colon.
colotomy n. (Music) The rhythmic and metric patterns of gamelan music, involving the use of specific instruments…
COLOTOMY n. a surgical incision of the colon.
KILOTONSkilotons n. Plural of kiloton.
KILOTON n. a measure of explosive force equivalent to that of 1000 tons of TNT, also KILOTONNE.
PELOTONSpelotons n. Plural of peloton.
PELOTON n. the main body of riders in a bicycle race.
XYLOTOMYxylotomy n. (Botany) The art of preparing sections of wood (as by means of a microtome) for microscopic examination.
XYLOTOMY n. the preparation of wood for microscopic examination.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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