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There are 2 eight-letter words containing IRRIT

IRRITANTirritant adj. Causing irritation or inflammation.
irritant adj. (Law, Scotland) Rendering null and void; conditionally invalidating.
irritant n. Any medication designed to cause irritation.
IRRITATEirritate v. (Transitive) To provoke impatience, anger, or displeasure in.
irritate v. (Intransitive) To cause or induce displeasure or irritation.
irritate v. (Transitive) To induce pain in (all or part of a body or organism).

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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