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There is only one eight-letter word containing IASTO

DIASTOLEdiastole n. (Chiefly uncountable, physiology) The phase or process of relaxation and dilation of the heart chambers…
diastole n. (Uncountable, prosody) The lengthening of a vowel or syllable beyond its typical length.
diastole n. (Greek grammar) The hypodiastole, a textual or punctuation mark formerly used to disambiguate homonyms in Greek.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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