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There are 4 fifteen-letter words containing ISTOC

BRACHISTOCHRONE	• brachistochrone n. (Mathematics) A cycloid; the curve of fastest descent between two points. • BRACHISTOCHRONE n. the curve along which a particle acted on by a force (e.g. gravity) will pass in the shortest time from one given point to another.
HISTOCHEMICALLY	• histochemically adv. By the use of histochemistry. • HISTOCHEMICAL adv. relating to histochemistry, the chemistry of living tissues.
HISTOCOMPATIBLE	• histocompatible adj. (Of two individuals) Having compatible antigens, and thus being able to transplant organs. • HISTOCOMPATIBLE adj. referring to the degree of similarity between the histocompatibility antigens of two individuals, which determines whether an organ transplant will be tolerated.
NONARISTOCRATIC	• nonaristocratic adj. Not aristocratic. • NONARISTOCRATIC adj. not aristocratic.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 15 words
Scrabble in French: 3 words
Scrabble in Spanish: 8 words
Scrabble in Italian: 3 words
Scrabble in German: no word
Scrabble in Romanian: 8 words

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