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There are 4 seven-letter words containing ISTU

DISTUNEdistune v. (Transitive) To put (something) out of tune.
distune v. (Transitive, figurative) To cause (something) not to be in harmony or to be poorly adjusted.
DISTUNE v. to put out of tune.
DISTURBdisturb v. (Transitive) to confuse a quiet, constant state or a calm, continuous flow, in particular: thoughts…
disturb v. (Transitive) to divert, redirect, or alter by disturbing.
disturb v. (Intransitive) to have a negative emotional impact; to cause emotional distress or confusion.
FISTULAfistula n. (Medicine) An abnormal connection or passageway between organs or vessels that normally do not connect.
fistula n. (Rare) A tube, a pipe, or a hole.
fistula n. (Christianity, historical) The tube through which the wine of the Eucharist was once sucked from the…
MISTUNEmistune v. (Transitive) To tune wrongly.
mistune n. An incorrect tuning.
MISTUNE v. to tune incorrectly.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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