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There are 5 seven-letter words containing ISEA

DEISEALdeiseal n. Motion towards the right, in the direction of the hands of a clock or of the apparent motion of the…
deiseal adv. Clockwise; sunwise.
deiseal interj. A deprecation meaning May it go right, said to someone who sneezes or swallows something awry.
DISEASEdisease n. (Medicine) An abnormal condition of a human, animal or plant that causes discomfort or dysfunction;…
disease n. (By extension) Any abnormal or harmful condition, as of society, people’s attitudes, way of living etc.
disease n. Lack of ease; uneasiness; trouble; vexation; disquiet.
MISEASEMISEASE n. (archaic) uneasiness.
MISEATSmiseats v. Third-person singular simple present indicative form of miseat.
MISEAT v. to eat improperly.
WISEASSwiseass n. One who makes wisecracks, particularly in a sassy or cocky fashion.
wise-ass n. Alternative spelling of wiseass.
WISEASS n. a pretentiously wise person, also WISEACRE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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