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There are 5 thirteen-letter words containing IOTO

ARTERIOTOMIESarteriotomies n. Plural of arteriotomy.
ARTERIOTOMY n. the surgical excision of an artery.
BACTERIOTOXINbacteriotoxin n. Any toxin produced by a bacterium.
bacteriotoxin n. Any material that is toxic to bacteria.
BACTERIOTOXIN n. a toxin of bacterial origin.
OVARIOTOMISTSovariotomists n. Plural of ovariotomist.
OVARIOTOMIST n. one who carries out ovariotomies.
RIOTOUSNESSESriotousnesses n. Plural of riotousness.
RIOTOUSNESS n. the state of being riotous.
SYMPHYSIOTOMYsymphysiotomy n. A surgical procedure in which the cartilage of the pubic symphysis is divided to widen the pelvis, allowing…
SYMPHYSIOTOMY n. the operation of cutting through the pubic symphysis, also SYMPHYSEOTOMY.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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