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There are 9 twelve-letter words containing ISEC

DISECONOMIESdiseconomies n. Plural of diseconomy.
DISECONOMY n. lack of economy; a factor responsible for an increase in cost.
MILLISECONDSmilliseconds n. Plural of millisecond.
MILLISECOND n. a thousandth part of a second.
QUADRISECTEDquadrisected v. Simple past tense and past participle of quadrisect.
QUADRISECT v. to divide into four equal parts.
TRISECTRICESTRISECTRIX n. a certain curve of a polar equation.
VENISECTIONSVENISECTION n. surgical incision into a vein.
VIVISECTIONSvivisections n. Plural of vivisection.
VIVISECTION n. the cutting of or operation on a living animal usually for physiological or pathological investigation.
VIVISECTORIAvivisectoria n. Plural of vivisectorium.
VIVISECTORIUM n. a place for vivisection.
WISECRACKERSwisecrackers n. Plural of wisecracker.
WISECRACKER n. one who wisecracks.
WISECRACKINGwisecracking adj. Making many wisecracks.
wisecracking v. Present participle of wisecrack.
wise-cracking adj. Alternative form of wisecracking.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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