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There are 4 twelve-letter words containing IOSA

ANGIOSARCOMAangiosarcoma n. (Oncology) Any malignant tumour of vascular tissue.
ANGIOSARCOMA n. a malignant tumour of the vascular epithelia, occurring e.g. in the liver.
BIOSATELLITEbiosatellite n. An artificial satellite that is designed to carry humans or other organisms.
BIOSATELLITE n. an artificial satellite containing living organisms to be studied during flight.
BRACHIOSAURSbrachiosaurs n. Plural of brachiosaur.
CRANIOSACRALcraniosacral adj. Of or pertaining to the cranium and sacrum, especially with regard to craniosacral therapy, a form of…
CRANIOSACRAL adj. as in craniosacral therapy, an alternative therapy involving gentle manipulation of the bones and membranes of the skull, in order to treat a wide range of physical and psychological disorders.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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