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There are 4 eleven-letter words containing IOTO

AMNIOTOMIESamniotomies n. Plural of amniotomy.
AMNIOTOMY n. surgical removal of the amnion.
ARTERIOTOMYarteriotomy n. (Medicine) The opening of an artery, especially for bloodletting.
ARTERIOTOMY n. the surgical excision of an artery.
CARDIOTONICcardiotonic adj. That has a favourable (tonic) effect on the action of the heart.
cardiotonic n. Any drug or substance having a tonic effect on the heart.
CARDIOTONIC n. a substance that tends to increase the tonus of heart muscle.
RIOTOUSNESSriotousness n. The state or condition of being riotous.
RIOTOUSNESS n. the state of being riotous.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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