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There are 4 eight-letter words containing GREN

GANGRENEgangrene n. The necrosis or rotting of flesh, usually caused by lack of blood supply.
gangrene n. (Figuratively) A damaging or corrupting influence.
gangrene v. (Transitive) To produce gangrene in.
GRENACHEgrenache n. A specific widely-planted variety of red wine grape, or a wine made from such grapes.
GRENACHE n. a kind of black grape; a red wine made from this.
GRENADESgrenades n. Plural of grenade.
GRENADE n. a small explosive shell designed to be thrown by hand or launched mechanically.
GRENNINGgrenning v. Present participle of gren.
GREN v. (Spenser) to grin.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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