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There are 2 eight-letter words containing ECULE

FECULENTfeculent adj. Dirty with faeces or other impurities.
FECULENT adj. full of filth or waste matter.
MOLECULEmolecule n. (Chemistry) The smallest particle of a specific element or compound that retains the chemical properties…
molecule n. A tiny amount.
MOLECULE n. the smallest unit of matter that has the chemical and physical properties of a particular chemical compound.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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