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There are 13 twelve-letter words containing ESIGN

DESIGNATIONSdesignations n. Plural of designation.
DESIGNATION n. the act of indicating or identifying.
OUTDESIGNINGoutdesigning v. Present participle of outdesign.
OUTDESIGN v. to surpass in designing.
OVERDESIGNEDoverdesigned adj. Having undergone excessive design, leading to complicatedness or an unnecessary degree of capability and durability.
OVERDESIGN v. to design to excess.
PREDESIGNATEpredesignate adj. Designated in advance.
predesignate adj. (Logic, of a proposition) Having its quantity indicated by a verbal sign, as with "all", "none", etc.
predesignate v. To designate in advance.
PREDESIGNINGpredesigning v. Present participle of predesign.
PREDESIGN v. to design in advance.
PRESIGNALINGPRESIGNAL v. to signal in advance.
PRESIGNALLEDPRESIGNAL v. to signal in advance.
PRESIGNIFIEDpresignified v. Simple past tense and past participle of presignify.
PRESIGNIFY v. to intimate or signify beforehand.
PRESIGNIFIESpresignifies v. Third-person singular simple present indicative form of presignify.
PRESIGNIFY v. to intimate or signify beforehand.
RESIGNATIONSresignations n. Plural of resignation.
RESIGNATION n. an act or instance of resigning something.
RESIGNEDNESSresignedness n. The state or condition of being resigned (passively accepting a situation).
RESIGNEDNESS n. the state of being resigned.
UNDESIGNATEDundesignated adj. Not designated.
UNDESIGNATED adj. not designated.
UNDESIGNEDLYundesignedly adv. In a way that was not designed; as an unexpected consequence; unintentionally.
UNDESIGNED adv. not designed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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