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There are 5 ten-letter words containing COLOS

COLOSSALLYcolossally adv. In a colossal manner, or to a colossal extent.
COLOSSAL adv. of enormous size.
COLOSSEUMScolosseums n. Plural of colosseum.
COLOSSEUM n. a large building or stadium used as a place of entertainment, also COLISEUM.
COLOSSUSEScolossuses n. Plural of colossus.
COLOSSUS n. (Latin) a person or organization of gigantic power and influence.
COLOSTROUScolostrous adj. Of or relating to colostrum.
COLOSTROUS adj. relating to colostrum, also COLOSTRAL, COLOSTRIC.
COLOSTRUMScolostrums n. Plural of colostrum.
COLOSTRUM n. (Latin) milk secreted for a few days after parturition, characterised by high protein and antibody content.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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