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There are 2 six-letter words containing ACULE

ACULEIaculei n. Plural of aculeus.
ACULEUS n. (Latin) a prickle growing on the bark, as in some brambles and roses.
MACULEmacule n. A spot.
macule n. A blur or an appearance of a double impression, as when the paper slips a little during printing.
macule v. (Printing) To blur or be blurred; especially to blur or double an impression from type.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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