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There is only one ten-letter word ending with OTHESIS

HYPOTHESIShypothesis n. (Sciences) Used loosely, a tentative conjecture explaining an observation, phenomenon or scientific…
hypothesis n. (General) An assumption taken to be true for the purpose of argument or investigation.
hypothesis n. (Grammar) The antecedent of a conditional statement.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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See this list for:

  • English Wiktionary: 4 words
  • Scrabble in French: no word
  • Scrabble in Spanish: no word
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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