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There is one word ending with IGUS

PEMPHIGUSpemphigus n. (Pathology) A severe autoimmune skin disease characterized by pustules and painful blisters, and which can be fatal.
PEMPHIGUS n. (Greek) a somewhat rare skin disease, characterized by the development of blebs upon different parts of the body, also PEMPHIX.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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