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There is only one twelve-letter word ending with GNIAS

SAPROLEGNIASSAPROLEGNIA n. any fungus of the genus Saprolegnia, one species of which grows on diseased salmon and was formerly thought to be the cause of the disease.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definition is a short excerpt from the 1Word.ws.

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