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There is one word ending with APULE

PAPULEpapule n. A small, inflammatory, irritated spot on the skin, similar in appearance to a pimple, but not containing pus.
PAPULE n. a pimple, also PAPULA.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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