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There are 17 words beginning with SIGNIFIC

SIGNIFICANCE	• significance n. The extent to which something matters; importance. • significance n. Meaning. • SIGNIFICANCE n. something that is conveyed as a meaning often obscurely or indirectly.
SIGNIFICANCES	• significances n. Plural of significance. • SIGNIFICANCE n. something that is conveyed as a meaning often obscurely or indirectly.
SIGNIFICANCIES	• significancies n. Plural of significancy. • SIGNIFICANCY n. significance.
SIGNIFICANCY	• significancy n. (Dated) significance. • SIGNIFICANCY n. significance.
SIGNIFICANT	• significant adj. Signifying something; carrying meaning. • significant adj. Having a covert or hidden meaning. • significant adj. Having a noticeable or major effect.
SIGNIFICANTLY	• significantly adv. In a significant manner or to a significant extent. • SIGNIFICANT adv. having meaning.
SIGNIFICANTS	• significants n. Plural of significant. • SIGNIFICANT n. something having meaning.
SIGNIFICATE	• significate n. (Logic) One of several things signified by a common term. • SIGNIFICATE n. a thing signified.
SIGNIFICATES	• significates n. Plural of significate. • SIGNIFICATE n. a thing signified.
SIGNIFICATION	• signification n. The act of signifying, or something that is signified; significance. • signification n. Evidence for the existence of something. • signification n. A meaning of a word.
SIGNIFICATIONS	• significations n. Plural of signification. • SIGNIFICATION n. the act of signifying.
SIGNIFICATIVE	• significative adj. (Usually followed by of) That tends to signify or indicate; indicative. • significative adj. That has meaning or significance; significant. • SIGNIFICATIVE adj. significant, suggestive.
SIGNIFICATIVELY	• significatively adv. In a significative manner. • SIGNIFICATIVE adv. significant, suggestive.
SIGNIFICATOR	• significator n. One who, or that which, signifies. • significator n. (Astrology) A planet that is supposed to rule something. • significator n. (Cartomancy) A card representing a querent, question, or situation.
SIGNIFICATORS	• significators n. Plural of significator. • SIGNIFICATOR n. in astrology, a planet ruling a house.
SIGNIFICATORY	• significatory adj. Significant; having signification. • SIGNIFICATORY adj. of or relating to a significator, in astrology, a planet ruling a house.
SIGNIFICS	• significs n. (Obsolete) A proposed linguistic science based on the use of the exact significance of terms and concepts. • SIGNIFICS n. the science of meaning.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 36 words
Scrabble in French: 6 words
Scrabble in Spanish: 53 words
Scrabble in Italian: 56 words
Scrabble in German: no word
Scrabble in Romanian: no word

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