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There are 2 eight-letter words beginning with SANGUI

SANGUIFYsanguify v. (Transitive, intransitive) To produce blood (from).
SANGUIFY v. to make blood.
SANGUINEsanguine adj. (Literary) Having the colour of blood; blood red.
sanguine adj. (Obsolete, physiology) Having a bodily constitution characterised by a preponderance of blood over the…
sanguine adj. Characterized by abundance and active circulation of blood.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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