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There are 3 eleven-letter words beginning with SUBSTI

SUBSTITUENT	• substituent n. (Chemistry) any atom, group, or radical substituted for another, or entering a molecule in place of… • substituent n. (Grammar) pro-form. • SUBSTITUENT n. a thing, esp. an atom, substituted for another.
SUBSTITUTED	• substituted v. Simple past tense and past participle of substitute. • SUBSTITUTE v. to put or use in the place of another.
SUBSTITUTES	• substitutes n. Plural of substitute. • substitutes v. Third-person singular simple present indicative form of substitute. • SUBSTITUTE v. to put or use in the place of another.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 7 words
Scrabble in French: 10 words
Scrabble in Spanish: 12 words
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: 26 words

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