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There are 15 seven-letter words beginning with SIGN

SIGNAGEsignage n. (Uncountable) Signs, particularly those imparting commercial, directional, or road traffic information…
signage n. (Countable, chiefly India, elsewhere regarded as nonstandard) A sign, a signboard.
SIGNAGE n. a system of signs in a community.
SIGNALSsignals n. Plural of signal.
signals v. Third-person singular simple present indicative form of signal.
SIGNAL v. to make a sign.
SIGNARYsignary n. The set of characters in a writing system: alphabet, syllabary, etc.
SIGNARY n. a system of signals.
SIGNEESsignees n. Plural of signee.
SIGNEE n. a signer of a document.
SIGNERSsigners n. Plural of signer.
SIGNER n. one that signs.
SIGNETSsignets n. Plural of signet.
SIGNET v. to mark with an official seal.
SIGNEURsigneur n. Obsolete spelling of seigneur.
SIGNEUR adj. (Shakespeare) senior.
SIGNIFYsignify v. To create a sign out of something.
signify v. To give (something) a meaning or an importance. (The addition of quotations indicative of this usage is being sought:)
signify v. To show one’s intentions with a sign etc.; to indicate, announce.
SIGNINGsigning n. The act of concluding a contract, especially by an athlete or entertainer with a company.
signing n. (By extension) A player signed by a sporting organization.
signing n. An event (signing session) in a bookshop etc. where an author signs copies of his or her book.
SIGNIORsignior n. Alternative form of signor.
SIGNIOR n. (Italian) an Italian title of courtesy for a man, also SIGNOR, SIGNORE.
SIGNORAsignora n. Mrs; madam; title of address or respect for women in Italy.
SIGNORA n. (Italian) an Italian title of courtesy for a married woman.
SIGNOREsignore n. Alternative form of signor.
SIGNORE n. (Italian) an Italian title of courtesy for a man, also SIGNOR, SIGNIOR.
SIGNORIsignori n. Plural of signor.
SIGNORE n. (Italian) an Italian title of courtesy for a man, also SIGNOR, SIGNIOR.
SIGNORSsignors n. Plural of signor.
SIGNOR n. (Italian) an Italian title of courtesy for a man, also SIGNIOR, SIGNORE.
SIGNORYsignory n. (Now rare) A territory or domain, especially under a feudal lordship.
signory n. Overlordship, dominion.
signory n. (Now historical) A ruling assembly, specifically of various Italian republics; a signoria.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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