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There are 4 five-letter words beginning with SPIC

SPICA	• spica n. (Botany) A spike. • spica n. (Ornithology) A spur. • spica n. A kind of bandage passing, by successive turns and crosses, from an extremity to the trunk; a spiral…
SPICE	• spice n. (Countable, uncountable) Aromatic or pungent plant matter (usually dried) used to season or flavour food. • spice n. (Uncountable) The quality of being spicy. • spice n. (Figurative, uncountable) Appeal, interest; an attribute that makes something appealing, interesting, or engaging.
SPICK	• spick n. Alternative spelling of spic. • spick n. (Obsolete) nail, a spike (slender piece of wood or metal, used as a fastener). • spick adj. Tidy; fresh.
SPICY	• spicy adj. Of, pertaining to, or containing spice. • spicy adj. (Of flavors) Provoking a burning sensation due to the presence of chilis or similar hot spices. • spicy adj. (Of flavors or odors) Tangy, zesty, or pungent.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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See this list for:

English Wiktionary: 8 words
Scrabble in French: 2 words
Scrabble in Spanish: no word
Scrabble in Italian: 2 words
Scrabble in German: 1 word
Scrabble in Romanian: 1 word

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